Ruiz i Altaba, A., Varnat, F. (2010). On hedgehogs and human cancer. Correspondence. /EMBO Molecular Medicine/. In press.

Mas, C., Ruiz i Altaba, A. (2010) Small molecule modulation of HH-GLI signaling: current leads, trials and tribulations. /Biochem. Pharmacol/. 80, 712-23.

Stecca, B., Ruiz i Altaba, A. (2010) Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals. /J. Mol. Cell Biol/. 2, 84-95.

Ruiz i Altaba, A. and Brand, A. (2009). Entity versus property: tracking the nature, genesis and role of stem cells in cancer. Conference on Stem cells and cancer. EMBO Reports 10: 832-836.

Ruiz i Altaba, A. (2008) Therapeutic inhibition of Hedgehog-GLI signaling in cancer: epithelial, stromal, or stem cell targets? Cancer Cell 14, 281-3.

Ruiz i Altaba, A., Mas, C. and Stecca, B. (2007) The Gli code: an information nexus regulating cell fate, stemness and cancer. Trends Cell Biology 17, 438-47.

Stecca, B. and Ruiz i Altaba, A. (2005). The brain as a paradigm of organ growth: Hedgehog-Gli signaling in stem cells and in brain tumors. J. Neurobiology 64:476-90

Sánchez, P., Clement, V. and Ruiz i Altaba, A. (2005). Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer. Cancer Research 65:2990-2992.

Ruiz i Altaba, A. (2005). Stem cells, regenerative medicine and a cure for cancer. L'Agefi Biotech. June 2005.

Stecca, B., Mas, C. and Ruiz i Altaba, A. (2005). Interference with HH-GLI1 signaling inhibits prostate cancer. Trends in Molecular Medicine 11, 199-203.

Ruiz i Altaba A., Stecca, B. and Sanchez, P. (2004). Shh-Gli signaling in brain tumors: stem cells and developmental programs in cancer. Cancer Letters - special issue. 204, 145-157.

Guerrero, I. and Ruiz i Altaba, A. (2003). Longing for ligand: hedgehog, patched and cell death. Science 301, 774-776.

Ruiz i Altaba, A., Nguyen, V. and Palma, V. (2003) The emerging design of the neural tube: Prepattern, Shh morphogen and Gli code. Current Opinion in Genetics and Development. 13, 513-521

Ruiz i Altaba A., Palma, V, and Dahmane, N. (2002) Hedgehog-Gli signaling and the growth of the brain. Nature Rev. Neurosci. 3:24-33.

Mullor, J, and Ruiz i Altaba, A. (2002) Hedgehog and the price of Gas. Bioessays. 24:22-26.

Ruiz i Altaba, A., Sanchez, P. and Dahmane, N. (2002) Gli and Hedgehog in cancer: tumors, embryos and stem cells. Nature Rev. Cancer. 2, 361-372.

Mullor, J.M., Sanchez, P. and Ruiz i Altaba, A. (2002) Pathways and consequences: Hedgehog signaling in human diesease. Trends in Cell Biology. 12, 562-569

Stecca, B. and Ruiz i Altaba, A. (2002). Therapeutic potential of modulators of the HH-GLI signaling pathway. J. Biology, 1:9.

Ruiz i Altaba, A., Gitton, Y. and Dahmane, N. (2001). Embryonic regionalization of the neocortex. Mechanisms of Development 107:3-11.

Ruiz i Altaba, A. (1999). The works of Gli and the power of Hedgehog. Nature Cell Biology. 1, 147-148.

Ruiz i Altaba, A. (1999) Gli proteins and Hedgehog signaling in development and cancer. Trends Genetics, 15, 418-425.

Ruiz i Altaba, A. (1999) The flower, the gene, the brain and the creative process- book review. Nature Genetics 22, 229-230.

Ruiz i Altaba, A. (1998) Deconstructing the organizer. Nature 391: 748-749.

Ruiz i Altaba, A. (1997) Catching a Gli-mpse of Hedgehog. Cell 90:193-196.

Ruiz i Altaba, A. (1994) Pattern Formation in the Vertebrate Neural Plate. Trends Neurosci. 17:233-243.

Ruiz i Altaba, A. and Jessell, T.M. (1993) Midline Cells and the Organization of the Vertebrate Neuraxis. Curr. Op. Gen. and Dev. 3:633-640.

Ruiz i Altaba, A. (1993) Induction and Axial Patterning of the Neural Plate: Planar and Vertical Signals. J. Neurobiology 24: 1276-1304.

Ruiz i Altaba, A. (1991) Vertebrate Development: an Emerging Synthesis. Trends Genetics 7:276-280.

Ruiz i Altaba, A. and Melton, D.A. (1990) Axis Formation and the Establishment of Polarity in Frog Embryos. Trends in Genetics 6:57-64.

 

 


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