Zbinden, M., Duquet, A., Lorente-Trigos, A., Ngwabyt, S.N., Borges, I., Ruiz i Altaba, A. (2010) NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53. /EMBO J/. [Epub ahead of print].

Varnat, F., Zacchetti, G., Ruiz i Altaba, A. (2009) Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling. /Mech Dev/. 127, 73-81.

Varnat, F., Duquet, A., Malerba, M., Zbinden, M., Mas, C., Gervaz, P. and Ruiz i Altaba, A. (2009) HEDGEHOG-GLI signaling is active in human epithelial tumor cells and is essential for colon cancer growth, recurrence, metastases and stem cell expansion. EMBO Molecular Medicine 1: 338-351.

Stecca, B. and Ruiz i Altaba, A. (2009). A GLI1-p53 inhibitory loop regulates neural stem and tumor cell numbers. EMBO J. 28, 663-676.

Arianna De Toni , Marie Zbinden, Jonathan A Epstein , Ariel Ruiz i Altaba, Alain Prochiantz and Isabell Caille (2008) Regulation of survival in adult hippocampal stem cell lineages by the homeodomain-only protein HOP. Neural Development 132:3267-3279.

Clement, V., Sanchez, P., De Tribolet, N., Radovanovic, I. and Ruiz i Altaba, A. (2007). Hedgehog-GLI signaling regulates human glioma growth, cancer stem cell self-renewal and tumorigenicity. Current Biology 17, 165-172.

Stecca, B., Mas, C., Clement, V., Zbinden, M., Correa, R., Piguet, V., Beermann, F. and Ruiz i Altaba (2007). Melanomas require Hedgehog-Gli signaling regulated by interactions between GLI1 an the RAS-MEK/AKT pathways. Proc. Natl. Acad. Sci. USA 104, 5895-5900.

Nguyen, V., Chokas, A.L., Stecca, B., Ruiz i Altaba. A. (2005) Cooperative requirement of the Gli proteins in neurogenesis. Development 132:3267-3279 .

Palma, V., Lim, D., Dahmane, Sanchez, P., Brionne, T.C, Herzberg, C.D., Gttton, Y., Carleton, A., Alvarez-Buylla, A. and Ruiz i Altaba, A. (2005) Shh-Gli signaling controls stem cell behavior in the postnatal and adult brain. Development 132, 335-344.

Sanchez P, Ruiz i Altaba A. (2005) In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice. Mechanisms of Development 122, 223-230.

Sanchez P, Hernandez AM, Stecca B, Kahler AJ, DeGueme AM, Barrett A, Beyna M, Datta MW, Datta S, Ruiz i Altaba A. (2004) Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling. Proc. Natl. Acad. Sci USA 101:12561-12566.

Palma, and Ruiz i Altaba, A. (2004) Hedgehog-Gli signaling controls the behavior of cells with stem cell properties in the developing neocortex. Development 131, 337-345.

Erich Roessler, Yangzu Du, Jose L. Mullor, Esther Casas, William P. Allen, Ian Ellis, Gabriele Gillessen-Kaesbach, Elizabeth R. Roeder, Jeffrey E. Ming, Ariel Ruiz i Altaba, Maximilian Muenke (2003) Loss-of-function mutations in the human GLI2 gene cause holoprosencephaly and familial pan-hypopituitarism. Proc. Natl. Acad. Sci. USA 100, 13424-13429.

Gitton, Y., Dahmane, N., Baik, S., Ruiz i Altaba, A. Neidhardt, L., Scholze, M., Herrmann, B., Kahlem, P., Kahla A., Schrinner, S., Yildirimman, R., Herwig, R., Lehrach, H. and Yaspo, M.L. (2002) A multi-level gene expression analysis of human chromosome 21 orthologs in the mouse: potential insights into Down syndrome. Nature 420, 586-590.

Dahmane, N., Sanchez, P., Gitton, Y., Palma, V., Sun, T., Weiner, H. and Ruiz i Altaba, A. (2001) The SHH-Gli pathway in brain growth and tumorigenesis. Development 128:5201-5212.

Mullor, J.L., Dahmane, N., Sun, T. and Ruiz i Altaba, A. (2001) Wnt signals are targets and mediators of Gli function. Current Biology 11, 769-773.

Brewster, R. and Ruiz i Altaba, A. (2000). Hexokinase I is a Gli2-responsive gene expressed in the embryonic CNS. Mech. Dev. 99, 159-162

Brewster, R., Mullor, J. and Ruiz i Altaba, A. (2000). Gli2 functions in FGF signaling during antero-posterior paterning. Development 127, 4395-4405.

Aza-Blanc, P., Lin, H-Y., Ruiz i Altaba, A. and Kornberg, T. (2000). Expression of vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities. Development 127, 4293-4301.

Ruiz i Altaba, A. (1999). Gli proteins encode context-dependent positive and negative functions: implications for development and disease. Development 126,3205-3216.

Dahmane, N. and Ruiz i Altaba, A. (1999). Sonic hedgehog regulates the growth and patterning of the cerebellum. Development 126, 3089-3100.

Ruiz i Altaba, A. (1998). Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog. Development 125, 2203-2212.

Liu, F., Massagué, J. & Ruiz i Altaba, A. (1998). Carboxy-terminally truncated Gli3 proteins associated with Smads. Nature Genetics 20:325-326.

Brewster, R., Lee, J. and Ruiz i Altaba, A. (1998) Gli/Zic factors pattern the neural plate by defining domains of cell differentiation. Nature 393, 579-583.

Nothias, F., Fishell, G. and Ruiz i Altaba, A. (1998) Cooperation of intrinsic and extrinsic signals in the determination of regional identity of the posterior neocortex. Curr. Biol. 8, 459-462

Dahmane, N., Lee, J., Robins, P., Heller, P. and Ruiz i Altaba, A. (1997) Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. Nature 389:876-881.

Lee, J., Platt, K., Censullo, P. and Ruiz i Altaba, A. (1997) Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development 124:2537-2552.

Ruiz i Altaba, A. and Théry, C. (1996) Involvement of Livertine, a hepatocyte growth factor family member, in neural morphogenesis. Mech. Dev. 60:207-220.

Ruiz i Altaba, A. (1996) Coexpression of HNF-3b and Isl-1/2 and mixed distribution of ventral cell types in the early neural tube. Int. J. Dev. Biol. 40:1081-1088.

Ruiz i Altaba, A., Roelink, H. and Jessell, T.M. (1995) Restrictions to Floor Plate Induction by hedgehog and Winged Helix Genes in the Neural Tube of Frog Embryos. Mol. Cell. Neurosci. 6:106-121.

Ruiz i Altaba, A. Placzek, M., Baldassare, M. Dodd, J. and Jessell, T.M. (1995) Early Stages of Notochord and Floor Plate Differentiation Defined by Normal and Induced Expression of HNF-3b in Chick Embryos. Dev. Biol. 170:299-313.